This Slow Cooked Mississippi Pot Roast is a dream come true! Tender beef, zesty ranch seasoning, and a punch of pepperoncini create a tasty mix that’s hard to resist.
Cooking this roast is almost like magic! Just throw everything in the slow cooker and let it do the work. I love serving it with mashed potatoes—so comforting!
Key Ingredients & Substitutions
Chuck Roast: This cut of meat is perfect for slow cooking as it becomes very tender and flavorful. If needed, you could substitute with brisket or round roast, but adjust cooking times accordingly since they may vary in tenderness.
Ranch Seasoning Mix: This adds a zesty flavor to the pot roast. If you don’t have it, you can mix together equal parts of garlic powder, dried dill, and onion powder for a homemade version.
Au Jus Gravy Mix: It gives a rich, beefy taste. In a pinch, you can use beef bouillon cubes dissolved in water or make your own gravy with beef broth and thickening agents like flour or cornstarch.
Pepperoncini Peppers: These add a delightful tang. If you don’t have them, you can use banana peppers or even sliced jalapeños for a bit of heat. Just remember to adjust the amount based on your spice preference!
How Do I Ensure My Pot Roast Comes Out Tender and Juicy?
The key to a perfect slow-cooked roast is low and slow cooking. Here’s how to get it right:
- Start with a nice sear on the roast in a hot skillet for added flavor, although it’s not mandatory.
- Keep the heat low and let it cook for a longer time—8 hours on low or 4-5 hours on high is ideal.
- Don’t lift the lid too often! Each time you open it, heat escapes and can prolong cooking.
- After cooking, shred the meat while it’s still warm and mix with the flavorful juices in the pot. This keeps the meat moist.
Serve with buns for easy eating, and enjoy the mouthwatering flavors of this comforting dish!

Slow Cooked Mississippi Pot Roast
Ingredients You’ll Need:
- 3 to 4 pounds chuck roast
- 1 packet (1 oz) ranch seasoning mix
- 1 packet (1 oz) au jus gravy mix
- 1/2 cup unsalted butter (1 stick)
- 5 to 7 pepperoncini peppers with some juice
- 1/2 cup beef broth or water
- 1 teaspoon garlic powder
- Fresh thyme or parsley (for garnish, optional)
- Hamburger buns or bread rolls (for serving)
- Optional: carrots or potatoes to slow cook along with roast
How Much Time Will You Need?
This recipe will take about 10-15 minutes to prepare and then either 8 hours on low or 4-5 hours on high in the slow cooker. It’s an easy, set-it-and-forget-it meal that’s perfect for busy days!
Step-by-Step Instructions:
1. Prepare the Roast
Start by placing the chuck roast right in your slow cooker. This is going to be the star of your meal! No need to worry about any cutting or trimming—you can go as is.
2. Add Seasonings
Next, sprinkle the ranch seasoning mix, au jus gravy mix, and garlic powder all over the roast. This will give it that fantastic flavor we love! The spices will melt into the meat as it cooks, making it absolutely delicious.
3. Layer the Goodness
Pop the stick of butter right on top of the roast. Trust me, it’ll make it moist and rich! Then, pour the beef broth around the sides of the roast (not over it) to keep those seasonings intact.
4. Topping Off with Peppers
Now, add the pepperoncini peppers (and some of the juice) on top. These little guys will add a perfect tang that complements the rich beef flavor.
5. Slow Cook It!
Cover your slow cooker and set it to cook on low for 8 hours or high for 4-5 hours. The longer, the better, as it will make the meat super tender and easy to shred.
6. Shred and Serve
Once it’s cooked and your kitchen smells amazing, take the roast out and shred it using two forks right inside the slow cooker. Mix the shredded meat with the juices to get all that flavor everywhere!
7. Enjoy!
Serve your delicious shredded beef on hamburger buns or bread rolls. Spoon some of that tasty juice over the meat for extra flavor, and don’t forget to garnish with fresh thyme or parsley if you like! If you’ve added carrots or potatoes, plate those up for a full meal.
Enjoy your tender, flavorful Mississippi Pot Roast sandwich!
Can I Use a Different Cut of Meat?
Absolutely! While chuck roast is ideal for its tenderness, you can also use brisket or round roast. Just remember that cooking times may vary depending on the cut, so keep an eye on it for tenderness.
How Do I Store Leftovers?
Store any leftover pot roast in an airtight container in the refrigerator for up to 3 days. You can freeze it for longer storage—just make sure it’s in a freezer-safe container or bag. Thaw in the fridge overnight before reheating.
Can I Add Vegetables to the Slow Cooker?
Yes, adding carrots, potatoes, or even onions can enhance the flavor! Just chop them into chunks and place them around the roast before cooking. They’ll soak up the juices and become wonderfully flavorful.
What Should I Serve with Mississippi Pot Roast?
This pot roast is delicious on its own or served on buns. Pair it with mashed potatoes, roasted vegetables, or a simple salad for a complete meal. Don’t forget to spoon the extra juices over everything for added flavor!
